Summary: The integration of oligonucleotides into medical research has opened up new doorways to recovery.
The mechanism of an oligonucleotide can be used for therapeutic purposes. The synthesis between the DNA and RNA polymers within the small molecular antiviral agents has been used in numerous important clinical drugs. However, the middle-man, the oligonucleotide, plays an important role in the production of these drugs as well.
The integration of oligos into antiviral therapeutic drugs has proved beneficial for both medicine and research purposes.
The Role of Antisense Oligonucleotides
Antisense oligonucleotides contribute to an agent by encoding the proteins that are vital for a virus or bacteria to survive. Essentially they assist by targeting the pathogens and supplying information necessary to eliminate foreign mRNA molecules.
By blocking the protein from synthesizing into normal cells, one can achieve information about the biological effect of the proteins. This alternate role proves that the antisense oligonucleotide is versatile and can also be utilized in a variety of situations.
The Application Process
Chemically unmodified antisense oligonucleotides will provide little to no guarantee of assistance to the subject. This is because an unmodified oligo does not provide significant antisense effect to a culture or an organism. Therefore, in order to solve this, antisense oligonucleotides must be chemically modified in order to maximize the antisense effect.
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