Entries by Erica Mitchell

Antisense Therapy is Changing Views on Diseases

Summary: Oligonucleotides are now being used as treatment options. With the help of radical technological breakthroughs, oligonucleotides, or oligos, are being used for therapeutic purposes. With the constant clamoring of how oligos can be used as a type of agent that will help deliver positive benefits to patients, it is now becoming more apparent that […]

The Role of Molecular Beacon Probes in RNA and DNA

Summary: Interest in molecular beacon probes is rapidly increasing. It has been known that molecular beacons have started arousing interest due their continuous readout, and outstanding spatial resolution when observed in real time. These kinds of dual-labeled probes have the ability to differentiate between two types of bound and unbound RNA and DNA in living […]

How Chemically-Modified Oligonucleotides Broadened the Research Field

Summary: Chemical modifications open up a whole new realm of opportunities for researchers. Oligonucleotides play an impactful role in a wide range of applications in fields like molecular biology, therapy, and biotechnology. Furthermore, they have also been studied and shaped into a therapeutic medication for viral infections. Their range of use can be further broadened […]

Antisense Therapy is Bringing New Life to the Biomedical World

Summary: Antisense oligonucleotides are playing large roles in disease prevention. Throughout the course of oligonucleotide history, major improvements and discoveries have been made in molecular biology that have allowed antisense therapy to thrive. This has allowed researchers to thrive in understanding diseases at the molecular level, which has essentially facilitated the development of new drugs […]

The Combinatorial Libraries of Oligonucleotides

Summary: To distinguish one member from another in the pool of oligos, a tagging system has been created. Over the last ten years, there has been significant improvement in the development of compound libraries for the discovery of molecules with new binding properties. The basic premise is to ultimately shorten the effort and time associated […]

Finding the Right Oligonucleotide Manufacturer

Oligonucleotide synthesis is essentially the synthesis of nucleic acid fragments that results in defined chemical structures with purities of different sizes. When you´re looking for the most effective modified product for your oligo synthesis, you´re going to want to narrow down the companies that you´re going to work with by high quality services that they […]

Fluorescent-labeled Oligonucleotides´ Role in Genetic Diseases

Summary: Oligonucleotides aid researchers in allocating certain issues within genetic diseases. Advanced techniques have greatly simplified labeling oligonucleotides and their conjugates. Studies have shown that they are now less tedious, more cost-efficient, and more effective than ever before. These new techniques have given researchers the ability to utilize moieties such as a fluorescent label that´s […]

Antisense Oligonucleotides for Therapeutic Research

Summary: The integration of oligonucleotides into medical research has opened up new doorways to recovery. The mechanism of an oligonucleotide can be used for therapeutic purposes. The synthesis between the DNA and RNA polymers within the small molecular antiviral agents has been used in numerous important clinical drugs. However, the middle-man, the oligonucleotide, plays an […]

The Significance of RNA Synthesis and Splicing

Summary: RNA synthesis shares a common origin with two ancient cells. To understand the process of RNA synthesis and splicing, there must be an introduction on the major factors that play a large role in the entire process. The process of RNA synthesis, or otherwise known as transcription, is a process that involves transcribing DNA […]

The Duties of DNA Polymers and How They Contribute To Research

Summary: The DNA polymer is an essential figure in the duplication process. What are DNA polymers? DNA polymerases are essentially enzymes that birth DNA molecules through the assembly of nucleotides, which are the building blocks of DNA. By working in conjunction with each other, usually in pairs, they have the ability to create two stands […]